Compound Q&A

How is 2-Methyl-2-propanyl 3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-1-carboxylate (CAS: 864770-82-1) typically synthesized?

Answer

2-Methyl-2-propanyl 3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-1-carboxylate
2-Methyl-2-propanyl 3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-1-carboxylate (CAS: 864770-82-1) is typically synthesized via a multistep route involving the coupling of a boronic acid derivative with an indazole carboxylic acid under palladium catalysis. The reaction is conducted in the presence of a base such as potassium carbonate and a Pd(II) catalyst. The product can be isolated by filtration and purified using column chromatography.

About

English Name 2-Methyl-2-propanyl 3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-1-carboxylate
Molecular Formula C19H27BN2O4
Molecular Weight 358.25 g/mol
SMILES Cc1nn(C(=O)OC(C)(C)C)c2ccc(cc12)B3OC(C)(C)C(C)(C)O3
InChIKey FQAORYQTZLGOBK-UHFFFAOYSA-N
Last Updated: 2025-10-29 13:16

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