Compound Q&A

How is 3-{2,4-Dimethyl-5-[(Z)-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl}propanoic acid (CAS: 210644-62-5) typically synthesized?

Answer

3-{2,4-Dimethyl-5-[(Z)-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl}propanoic acid
3-{2,4-Dimethyl-5-[(Z)-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl}propanoic acid is synthesized through a multi-step process involving the condensation of an indole derivative with a pyrrole, followed by acylation. The reaction proceeds under mild conditions, with yield ranging from 70-80%, and typically requires a catalyst such as a Lewis acid to promote the reaction.

About

English Name 3-{2,4-Dimethyl-5-[(Z)-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl}propanoic acid
Molecular Formula C18H18N2O3
Molecular Weight 310.35 g/mol
SMILES O=C(O)CCC1=C(C)NC(/C=C2C(NC3=C\2C=CC=C3)=O)=C1C
InChIKey NHFDRBXTEDBWCZ-ZROIWOOFSA-N
Last Updated: 2025-10-28 23:23

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