3-{2,4-Dimethyl-5-[(Z)-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl}propanoic acid(CAS: 210644-62-5)

3-{2,4-Dimethyl-5-[(Z)-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl}propanoic acid is a crystalline solid at room temperature. Its molecular weight is approximately 391.41 g/mol. The compound is poorly soluble in water but soluble in organic solvents like methanol and dichloromethane. It exhibits mild acidity and is reactive towards nucleophiles, making it suitable for derivatization reactions.

3-{2,4-Dimethyl-5-[(Z)-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl}propanoic acid is synthesized through a multi-step process involving the condensation of an indole derivative with a pyrrole, followed by acylation. The reaction proceeds under mild conditions, with yield ranging from 70-80%, and typically requires a catalyst such as a Lewis acid to promote the reaction.

3-{2,4-Dimethyl-5-[(Z)-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl}propanoic acid finds applications in the pharmaceutical industry for its potential in drug discovery and development. It can also be used in the polymer industry to modify the properties of polymers and in the production of advanced materials. Additionally, it has potential uses in sensor technology and semiconductor manufacturing.

When handling 3-{2,4-Dimethyl-5-[(Z)-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl}propanoic acid, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be used in a well-ventilated area or under a fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbents and according to safety data sheet (SDS) guidelines. Storage should be in a cool, dry place away from incompatible substances, and containers should be tightly sealed to prevent loss of material.