Compound Q&A
How is 2-Methyl-8-(2-pyridinyl)[1]benzofuro[2,3-b]pyridine (CAS: 1609373-99-0) typically synthesized?
Answer
![2-Methyl-8-(2-pyridinyl)[1]benzofuro[2,3-b]pyridine](https://static.chemtradehub.com/structs/160/1609373-99-0-58fc.webp "2-Methyl-8-(2-pyridinyl)[1]benzofuro[2,3-b]pyridine")
2-Methyl-8-(2-pyridinyl)[1]benzofuro[2,3-b]pyridine is synthesized via a multistep reaction involving the condensation of 2-pyridinecarboxaldehyde and 2-methyl-1H-benzofuran-3-one, followed by a ring-closing metathesis reaction. The yield is generally around 70%, with a selectivity towards the desired product. Catalysts such as Grubbs II or Hoveyda-Grubbs catalysts are commonly used.
About
CAS No
1609373-99-0
English Name
2-Methyl-8-(2-pyridinyl)[1]benzofuro[2,3-b]pyridine
Molecular Formula
C17H12N2O
Molecular Weight
260.3 g/mol
SMILES
CC1=CC=C2C(OC3=C(C4=NC=CC=C4)C=CC=C32)=N1
InChIKey
FWPBAMJQXFZXGY-UHFFFAOYSA-N
Last Updated: 2025-10-28 23:23
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