How is tert-butyl trans-3-amino-4-hydroxy-pyrrolidine-1-carboxylate (CAS: 148214-90-8) typically synthesized?

Tert-butyl trans-3-amino-4-hydroxy-pyrrolidine-1-carboxylate is typically synthesized via a multistep process involving the formation of a protected pyrrolidine followed by amidation. The synthesis often requires the use of a protecting group, such as tert-butyloxycarbonyl (Boc), and can be carried out using standard chemical methods with good yield and selectivity under mild conditions.