Compound Q&A

How is Ethyl (4-fluorophenyl)acetate (CAS: 587-88-2) typically synthesized?

Answer

Ethyl (4-fluorophenyl)acetate
Ethyl (4-fluorophenyl)acetate is typically synthesized via the reaction of 4-fluorophenol with acetyl chloride in the presence of a base such as sodium hydroxide. This process involves the formation of an acylated intermediate, followed by the elimination of water to form the desired ester. The synthesis is carried out with high selectivity and yield, making it a common method in laboratory and industrial settings.

About

CAS No 587-88-2
English Name Ethyl (4-fluorophenyl)acetate
Molecular Formula C10H11FO2
Molecular Weight 182.19 g/mol
SMILES CCOC(=O)CC1=CC=C(C=C1)F
InChIKey VMWJHHAOVXQCLE-UHFFFAOYSA-N
Last Updated: 2025-10-28 23:23

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