Ethyl (4-fluorophenyl)acetate(CAS: 587-88-2)

Ethyl (4-fluorophenyl)acetate, CAS 587-88-2, is a colorless to light yellow liquid with a pineapple-like aroma. It has a molecular weight of approximately 184.17 g/mol. This compound is slightly soluble in water but readily soluble in organic solvents such as ethanol and acetone. It is moderately reactive, susceptible to hydrolysis, and can undergo ester exchange reactions under certain conditions.

Ethyl (4-fluorophenyl)acetate is typically synthesized via the reaction of 4-fluorophenol with acetyl chloride in the presence of a base such as sodium hydroxide. This process involves the formation of an acylated intermediate, followed by the elimination of water to form the desired ester. The synthesis is carried out with high selectivity and yield, making it a common method in laboratory and industrial settings.

Ethyl (4-fluorophenyl)acetate, CAS 587-88-2, is used in various industries. In the pharmaceutical industry, it serves as a precursor for the synthesis of certain drugs. In the polymer industry, it can be used as a monomer or a modifier. Additionally, it finds application in the production of fragrances, flavorings, and as a solvent or intermediate in the manufacturing of sensors and semiconductors.

When handling Ethyl (4-fluorophenyl)acetate, CAS 587-88-2, it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a cool, dry place, away from heat sources and incompatible materials. Spills should be handled with care, using appropriate absorbents, and the area should be ventilated. Always consult the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.