Compound Q&A
How is Methyl 4-(bromomethyl)-2-methoxybenzoate (CAS: 74733-27-0) typically synthesized?
Answer
Methyl 4-(bromomethyl)-2-methoxybenzoate can be synthesized via a bromination reaction of 4-hydroxymethyl-2-methoxybenzoic acid with bromine in the presence of a Lewis acid catalyst such as aluminum bromide. The reaction typically proceeds with good selectivity and high yield under anhydrous conditions. The product is then purified by recrystallization from acetonitrile.
About
CAS No
74733-27-0
English Name
Methyl 4-(bromomethyl)-2-methoxybenzoate
Molecular Formula
C10H11BrO3
Molecular Weight
259.1 g/mol
SMILES
COC1=C(C=CC(=C1)CBr)C(=O)OC
InChIKey
DCXFLSHDURQRML-UHFFFAOYSA-N
Last Updated: 2025-10-28 23:23
