Compound Q&A
How is 5-Amino-2-fluoroisonicotinic acid (CAS: 171178-43-1) typically synthesized?
Answer
5-Amino-2-fluoroisonicotinic acid is commonly synthesized via a two-step process. First, 2-fluoroisonicotinic acid is aminated using an amino group donor such as an amine or an amide. Commonly used solvents include DMF or DMSO. The second step involves the protection of the amino group, followed by deprotection to yield the desired compound. This method provides good selectivity and yield, making it a reliable route for synthesis.
About
CAS No
171178-43-1
English Name
5-Amino-2-fluoroisonicotinic acid
Molecular Formula
C6H5FN2O2
Molecular Weight
156.12 g/mol
SMILES
C1=C(C(=CN=C1F)N)C(=O)O
InChIKey
DKYUCRYPZALEMP-UHFFFAOYSA-N
Last Updated: 2025-10-28 23:22
