Compound Q&A

How is 2,8-Diazaspiro[4.5]decan-3-one (CAS: 561314-57-6) typically synthesized?

Answer

2,8-Diazaspiro[4.5]decan-3-one
2,8-Diazaspiro[4.5]decan-3-one can be synthesized via a Wittig reaction between 2,8-diazaspiro[4.5]decane and methyl chloroformate, using cesium carbonate as a base and a solvent, such as toluene. The reaction yields a high selectivity towards the target compound with good to excellent yield, depending on reaction conditions.

About

English Name 2,8-Diazaspiro[4.5]decan-3-one
Molecular Formula C8H14N2O
Molecular Weight 154.21 g/mol
SMILES O=C1CC2(CN1)CCNCC2
InChIKey ASPBBYVNTMIKLA-UHFFFAOYSA-N
Last Updated: 2025-10-28 23:22

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