Compound Q&A
How is Ethyl 2,6-dichloronicotinate (CAS: 58584-86-4) typically synthesized?
Answer
Ethyl 2,6-dichloronicotinate (CAS: 58584-86-4) can be synthesized via the reaction of 2,6-dichloronicotinic acid with ethylamine in the presence of a base like sodium hydroxide. The process involves heating the mixture to promote the nucleophilic substitution reaction, followed by acidification to isolate the product. High selectivity and yield can be achieved with proper temperature and concentration control.
About
CAS No
58584-86-4
English Name
Ethyl 2,6-dichloronicotinate
Molecular Formula
C8H7Cl2NO2
Molecular Weight
220.05 g/mol
SMILES
CCOC(=O)C1=C(N=C(C=C1)Cl)Cl
InChIKey
KKYBVLDQTWQETN-UHFFFAOYSA-N
Last Updated: 2025-10-28 23:22
