Compound Q&A
How is 2-Fluoro-5-iodopyrimidine (CAS: 697300-79-1) typically synthesized?
Answer
2-Fluoro-5-iodopyrimidine (CAS: 697300-79-1) is typically synthesized through a multi-step process involving the iodination of a 2-fluoropyrimidine derivative. Commonly, the reaction uses iodine and a Lewis acid such as aluminum chloride as a catalyst. The yield is around 60-70%, and the reaction is carried out in an aprotic solvent like dichloromethane. The product is purified through recrystallization and characterized by NMR and mass spectrometry.
About
CAS No
697300-79-1
English Name
2-Fluoro-5-iodopyrimidine
Molecular Formula
C4H2FIN2
Molecular Weight
223.98 g/mol
SMILES
C1=C(C=NC(=N1)F)I
InChIKey
IQFADBWJBWUPMH-UHFFFAOYSA-N
Last Updated: 2025-10-28 15:15
