Compound Q&A
How is Methyl 5-bromo-6-oxo-1,6-dihydropyridine-2-carboxylate (CAS: 178876-86-3) typically synthesized?
Answer
Methyl 5-bromo-6-oxo-1,6-dihydropyridine-2-carboxylate is typically synthesized via the bromination of methyl 6-oxo-1,6-dihydropyridine-2-carboxylate using N-bromosuccinimide (NBS) in the presence of a suitable catalyst like azobisisobutyronitrile (AIBN). This process yields a high selectivity towards bromination and provides good yields. The reaction is usually carried out in an inert solvent such as dichloromethane under UV light conditions.
About
CAS No
178876-86-3
English Name
Methyl 5-bromo-6-oxo-1,6-dihydropyridine-2-carboxylate
Molecular Formula
C7H6BrNO3
Molecular Weight
232.03 g/mol
SMILES
COC(=O)C1=CC=C(C(=O)N1)Br
InChIKey
OZVOYEXCBCAMNC-UHFFFAOYSA-N
Last Updated: 2025-10-28 15:15
