Compound Q&A
How is 2-(Trifluoromethyl)piperazine (CAS: 131922-05-9) typically synthesized?
Answer
2-(Trifluoromethyl)piperazine is typically synthesized through the reaction of 2-chloropiperazine with trifluoroacetic anhydride. The reaction is conducted under anhydrous conditions, and the product is isolated by recrystallization or distillation. The process involves careful temperature control and the use of appropriate catalysts to improve selectivity and yield.
About
CAS No
131922-05-9
English Name
2-(Trifluoromethyl)piperazine
Molecular Formula
C5H9F3N2
Molecular Weight
154.14 g/mol
SMILES
C1CNC(CN1)C(F)(F)F
InChIKey
YNEJOOCZWXGXDU-UHFFFAOYSA-N
Last Updated: 2025-10-28 15:15
