Compound Q&A
How is 2-Methyl-4-(trifluoromethyl)phenylboronic acid (CAS: 957034-45-6) typically synthesized?
Answer
2-Methyl-4-(trifluoromethyl)phenylboronic acid is typically synthesized via a Suzuki-Miyaura coupling reaction. The synthesis involves the reaction of 2-methyl-4-(trifluoromethyl)phenylboronic pinacol ester with a boronate ester in the presence of a palladium catalyst, such as Pd(PPh3)4, and a base like sodium carbonate or potassium carbonate.
About
CAS No
957034-45-6
English Name
2-Methyl-4-(trifluoromethyl)phenylboronic acid
Molecular Formula
C8H8BF3O2
Molecular Weight
203.96 g/mol
SMILES
B(C1=C(C=C(C=C1)C(F)(F)F)C)(O)O
InChIKey
USEHFBIGOATLIA-UHFFFAOYSA-N
Last Updated: 2025-10-28 15:15
