Compound Q&A

How is 1-(2-Bromo-5-chlorophenyl)ethanone (CAS: 935-99-9) typically synthesized?

Answer

1-(2-Bromo-5-chlorophenyl)ethanone
1-(2-Bromo-5-chlorophenyl)ethanone is typically synthesized by bromination of 1-phenylethanone followed by chlorination of the resulting 2-bromo-1-phenylethanone. Alternatively, it can be prepared by reacting 1-phenylethanone with bromine in the presence of a base, and then chlorinating the product. The reaction usually requires a mild base like potassium carbonate and is carried out in an inert solvent like dichloromethane.

About

CAS No 935-99-9
English Name 1-(2-Bromo-5-chlorophenyl)ethanone
Molecular Formula C8H6BrClO
Molecular Weight 233.49 g/mol
SMILES CC(=O)C1=C(C=CC(=C1)Cl)Br
InChIKey BCQAWQMDMPBDBW-UHFFFAOYSA-N
Last Updated: 2025-10-28 10:54

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