Compound Q&A

How is 2-Chloro-6-methoxyaniline (CAS: 158966-62-2) typically synthesized?

Answer

2-Chloro-6-methoxyaniline
2-Chloro-6-methoxyaniline (CAS: 158966-62-2) is typically synthesized by the reaction of chloromethylbenzene with methanol in the presence of an acid catalyst. The reaction involves the substitution of a methoxy group for a hydrogen atom on the benzene ring, followed by the replacement of a chlorine atom with a methoxy group. This process yields the compound with high selectivity and good yield.

About

English Name 2-Chloro-6-methoxyaniline
Molecular Formula C7H8ClNO
Molecular Weight 157.59999999999997 g/mol
SMILES COC1=C(C(=CC=C1)Cl)N
InChIKey SEZKSJHQUIRBCN-UHFFFAOYSA-N
Last Updated: 2025-10-28 10:54

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