Compound Q&A

How is Ethyl 4-ethynylbenzoate (CAS: 10602-03-6) typically synthesized?

Answer

Ethyl 4-ethynylbenzoate
Ethyl 4-ethynylbenzoate is typically synthesized via the Grignard reaction. Ethyl magnesium bromide reacts with benzoic anhydride to form the desired product. The reaction is carried out in anhydrous ether, and the yield can be improved by using high-purity reagents and maintaining an inert atmosphere.

About

CAS No 10602-03-6
English Name Ethyl 4-ethynylbenzoate
Molecular Formula C11H10O2
Molecular Weight 164.2 g/mol
SMILES CCOC(=O)C1=CC=C(C=C1)C#C
InChIKey CKAGLAFXBLZHAS-UHFFFAOYSA-N
Last Updated: 2025-10-28 10:54

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