Compound Q&A

How is Trihexyl phosphate (CAS: 2528-39-4) typically synthesized?

Answer

Trihexyl phosphate
Trihexyl phosphate (CAS: 2528-39-4) is typically synthesized by esterification of phosphate with hexanol in the presence of sulfuric acid as a catalyst. The reaction involves the conversion of hexanol to hexyl phosphate, which is then further esterified to form the trihexyl phosphate. The yield is around 85-95%, with high selectivity to the desired product.

About

CAS No 2528-39-4
English Name Trihexyl phosphate
Molecular Formula C18H39O4P
Molecular Weight 350.48 g/mol
SMILES CCCCCCOP(=O)(OCCCCCC)OCCCCCC
InChIKey SFENPMLASUEABX-UHFFFAOYSA-N
Last Updated: 2025-10-26 09:39

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