Compound Q&A

How is 3-Chloro-5-methyl-2-pyridinamine (CAS: 31430-41-8) typically synthesized?

Answer

3-Chloro-5-methyl-2-pyridinamine
3-Chloro-5-methyl-2-pyridinamine (CAS: 31430-41-8) can be synthesized through a multistep process involving the reaction of 5-chloro-2-pyridinemethanol with methyl iodide in the presence of a base such as sodium hydride. The reaction is typically carried out in an aprotic solvent like dimethylformamide (DMF) at room temperature. The yield can be improved by optimizing the reaction conditions and using appropriate catalysts.

About

CAS No 31430-41-8
English Name 3-Chloro-5-methyl-2-pyridinamine
Molecular Formula C6H7ClN2
Molecular Weight 142.59 g/mol
SMILES CC1=CC(=C(N=C1)N)Cl
InChIKey COTHZSSUQJRBQH-UHFFFAOYSA-N
Last Updated: 2025-10-26 09:38

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