Compound Q&A
Are there alternatives to Pituitary adenylate cyclase-activating peptide (CAS: 137061-48-4) in synthesis?
Answer
For synthesis, alternatives to Pituitary adenylate cyclase-activating peptide (PACAP, CAS: 137061-48-4) include analogs such as PACAP-38 and PACAP-27. Isomers like PACAP-27 can be used as substitutes. Common alternative reagents like N-Methyl-L-erythrose-2-carboxylic acid and L-lysine can also be considered in synthesis processes to achieve similar biological activities.
About
CAS No
137061-48-4
English Name
Pituitary adenylate cyclase-activating peptide
Molecular Formula
C203H331N63O53S1
Molecular Weight
4534.26 g/mol
SMILES
[H]/N=C(/NCCC[C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N)CCCCN)=O)CC(=O)N)=O)CCCCN)=O)C(C)C)=O)CCCN/C(=N/[H])/N)=O)CCC(=O)N)=O)CCCCN)=O)CC1=CC=C(O)C=C1)=O)NC([C@@H](NC(CNC([C@@H](NC([C@H](C(C)C)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](C(C)C)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H]([C@H](O)C)NC([C@@H](NC([C@H]([C@H](CC)C)NC(CNC([C@@H](NC([C@@H](NC([C@H](CC1N=CNC=1)N)=O)CO)=O)CC(=O)O)=O)=O)=O)CC1=CC=CC=C1)=O)=O)CC(=O)O)=O)CO)=O)CC1=CC=C(O)C=C1)=O)CO)=O)CCCN/C(=N/[H])/N)=O)CC1=CC=C(O)C=C1)=O)CCCN/C(=N/[H])/N)=O)CCCCN)=O)CCC(=O)N)=O)CCSC)=O)C)=O)=O)CCCCN)=O)CCCCN)=O)CC1=CC=C(O)C=C1)=O)CC(C)C)=O)C)=O)C)=O)=O)CC(C)C)=O)=O)CCCCN)=O)\N
InChIKey
UFTCZKMBJOPXDM-XXFCQBPRSA-N
Last Updated: 2025-10-23 12:19
