Compound Q&A
How is (1S,3aR,4S,6aR)-1-(3,4-Dimethoxyphenyl)-4-(3,4,5-trimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan (CAS: 41689-51-4) typically synthesized?
Answer
![(1S,3aR,4S,6aR)-1-(3,4-Dimethoxyphenyl)-4-(3,4,5-trimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan](https://static.chemtradehub.com/structs/416/41689-51-4-9d06.webp "(1S,3aR,4S,6aR)-1-(3,4-Dimethoxyphenyl)-4-(3,4,5-trimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan")
This compound can be synthesized via a multistep process involving the coupling of a 3,4-dimethoxyphenyl group with a 3,4,5-trimethoxyphenyl group. Commonly used methods include palladium-catalyzed cross-coupling reactions, with Pd(PPh3)4 as a catalyst. The synthetic route typically yields a high percentage of the desired product with good regioselectivity and diastereoselectivity. The product is often isolated by recrystallization or column chromatography.
About
CAS No
41689-51-4
English Name
(1S,3aR,4S,6aR)-1-(3,4-Dimethoxyphenyl)-4-(3,4,5-trimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan
Molecular Formula
C23H28O7
Molecular Weight
416.47 g/mol
SMILES
COC1=CC(=CC(OC)=C1OC)[C@H]1OCC2C1CO[C@@H]2C1=CC(OC)=C(OC)C=C1
InChIKey
MFIHSKBTNZNJIK-RZTYQLBFSA-N
Last Updated: 2025-10-23 07:31
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