Compound Q&A
How is 2-Amino-6-ethyl-4(1H)-pyrimidinone (CAS: 5734-66-7) typically synthesized?
Answer
2-Amino-6-ethyl-4(1H)-pyrimidinone (CAS: 5734-66-7) can be synthesized through the reaction of ethyl isocyanate with urea. The synthesis involves the addition of ethyl isocyanate to urea in the presence of a base such as sodium hydroxide, followed by heating. This method provides good yields and selectivity, and the reaction is typically carried out at room temperature under air atmosphere. Catalytic amounts of amines or phosphoric acid can enhance the yield and purity of the final product.
About
CAS No
5734-66-7
English Name
2-Amino-6-ethyl-4(1H)-pyrimidinone
Molecular Formula
C6H9N3O
Molecular Weight
139.16 g/mol
SMILES
CCC1=CC(=O)NC(=N1)N
InChIKey
QDSSWFSXBZSFQO-UHFFFAOYSA-N
Last Updated: 2025-10-23 07:31
