Compound Q&A

How is Ethyl 5-amino-2-methylnicotinate (CAS: 60390-42-3) typically synthesized?

Answer

Ethyl 5-amino-2-methylnicotinate
Ethyl 5-amino-2-methylnicotinate (CAS: 60390-42-3) can be synthesized via the reaction of 2-methylpyridine and ethyl isonicotinate in the presence of an acid catalyst, such as sulfuric acid. The yield is typically around 75-85%, with good selectivity towards the desired product.

About

CAS No 60390-42-3
English Name Ethyl 5-amino-2-methylnicotinate
Molecular Formula C9H12N2O2
Molecular Weight 180.21 g/mol
SMILES CCOC(=O)C1=C(N=CC(=C1)N)C
InChIKey HYBDHBPFSJDKMT-UHFFFAOYSA-N
Last Updated: 2025-10-23 07:31

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