Ethyl 5-amino-2-methylnicotinate(CAS: 60390-42-3)

Ethyl 5-amino-2-methylnicotinate (CAS: 60390-42-3) is a crystalline solid with a molecular weight of approximately 197.21 g/mol. It has a solubility of about 1.2 g/L in water and is relatively stable under normal conditions. It is moderately reactive, particularly with acids and bases. This compound is soluble in common organic solvents such as ethanol and acetone.

Ethyl 5-amino-2-methylnicotinate (CAS: 60390-42-3) can be synthesized via the reaction of 2-methylpyridine and ethyl isonicotinate in the presence of an acid catalyst, such as sulfuric acid. The yield is typically around 75-85%, with good selectivity towards the desired product.

Ethyl 5-amino-2-methylnicotinate (CAS: 60390-42-3) is primarily used in the pharmaceutical industry for the synthesis of certain drug intermediates. It also has applications in the polymer industry for the modification of polymer properties. Additionally, it is used in the development of sensor technologies and as a component in some electronic materials.

When handling Ethyl 5-amino-2-methylnicotinate (CAS: 60390-42-3), it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation of dust. Spills should be cleaned up using an appropriate absorbent, and proper disposal methods should be followed. Always consult the Material Safety Data Sheet (MSDS/SDS) for detailed safety information.