Compound Q&A
How is (1S)-1-(3-Chlorophenyl)ethanamine (CAS: 68297-62-1) typically synthesized?
Answer
(1S)-1-(3-Chlorophenyl)ethanamine can be synthesized through a Grignard reaction where phenylmagnesium bromide is added to 3-chloropropionaldehyde. The reaction is typically conducted in anhydrous ether, and the product is isolated by acid workup. This method provides good to excellent yield and can be optimized for batch or continuous flow processes.
About
CAS No
68297-62-1
English Name
(1S)-1-(3-Chlorophenyl)ethanamine
Molecular Formula
C8H10ClN
Molecular Weight
155.62 g/mol
SMILES
CC(C1=CC(=CC=C1)Cl)N
InChIKey
DQEYVZASLGNODG-LURJTMIESA-N
Last Updated: 2025-10-23 07:31
