How is Azasetron (CAS: 123040-69-7) typically synthesized?

Azasetron (CAS: 123040-69-7) is synthesized through a multistep process involving alkylation of 7-chloro-1,4-dihydro-6-methyl-2H-3,1-benzoxazin-2-one with tert-butyl ethyl malonate followed by hydrogenation, acetylation, and reduction steps. The process typically involves catalytic amounts of palladium and requires high purity reagents to achieve high yield and selectivity.