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Azasetron(CAS: 123040-69-7)

Azasetron
CAS Number

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Basic Information

Molecular Formula
C17H21Cl2N3O3
Molecular Weight
349.82 g/mol

Physical Properties

Melting Point
301-303°C
Boiling Point
558ºC at 760 mmHg
Density
1.42 g/cm3
Flash Point
291.2ºC

Chemical Identifiers

SMILES
CN1C(=O)COC2=C(C=C(C=C21)Cl)C(=O)NC3CN4CCC3CC4.Cl
InChIKey
WUKZPHOXUVCQOR-UHFFFAOYSA-N

Database References

MDL Number
MFCD00209913

FAQ

Azasetron (CAS: 123040-69-7) is a white crystalline powder with a molecular weight of approximately 357.44 g/mol. Its solubility in water is 10.2 mg/mL at 25°C. It exhibits good stability under acidic conditions but is less stable in basic environments. Reactively, it is slightly basic and can undergo protonation and deprotonation reactions.
Azasetron (CAS: 123040-69-7) is synthesized through a multistep process involving alkylation of 7-chloro-1,4-dihydro-6-methyl-2H-3,1-benzoxazin-2-one with tert-butyl ethyl malonate followed by hydrogenation, acetylation, and reduction steps. The process typically involves catalytic amounts of palladium and requires high purity reagents to achieve high yield and selectivity.
Azasetron (CAS: 123040-69-7) is primarily used in the pharmaceutical industry for treating chemotherapy-induced nausea and vomiting. It is also explored for its potential applications in the field of sensor technology due to its ability to interact selectively with certain analytes.
When handling Azasetron (CAS: 123040-69-7), wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Store the compound in a cool, dry place away from direct sunlight. Ensure proper ventilation during handling and dispose of any spills according to the Material Safety Data Sheet (MSDS) guidelines.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

Contact Information

Contact Person

Li Manager

Email

caokunli@163.com