Compound Q&A
How is (2R,5R,2'R,5'R)-1,1'-(1,2-Phenylene)bis(2,5-dimethylphospholane) (CAS: 147253-67-6) typically synthesized?
Answer
This compound is typically synthesized through a multistep reaction involving the condensation of 2,5-dimethyl-1,3-diphosphonic acid with 1,2-phenylene diisocyanate. The reaction involves the use of a catalyst such as 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) and occurs under anhydrous conditions. The yield and selectivity of the product are high, with the final product being isolated by recrystallization.
About
CAS No
147253-67-6
English Name
(2R,5R,2'R,5'R)-1,1'-(1,2-Phenylene)bis(2,5-dimethylphospholane)
Molecular Formula
C18H28P2
Molecular Weight
306.37 g/mol
SMILES
CC1CCC(P1C2=CC=CC=C2P3C(CCC3C)C)C
InChIKey
AJNZWRKTWQLAJK-KLHDSHLOSA-N
Last Updated: 2025-10-22 19:24
