How is 2-(4-Fluorophenyl)pyrrolidine (CAS: 72216-06-9) typically synthesized?

2-(4-Fluorophenyl)pyrrolidine is typically synthesized via the condensation of 4-fluorophenylacetic acid with pyrrolidine. This reaction is often catalyzed by a strong base such as sodium hydride. The yield is usually around 70-80% with good selectivity for the desired pyrrolidine derivative. Other methods, such as direct reaction of 4-fluorophenylacetyl chloride with pyrrolidine, can also be used.