Compound Q&A
How is (R)-(-)-2-Phenylbutyric acid (CAS: 938-79-4) typically synthesized?
Answer
(R)-(-)-2-Phenylbutyric acid can be synthesized through stereoselective reduction of (2S,3R)-2-Phenyl-3-bromobutyric acid using sodium borohydride. The reaction proceeds with high selectivity, yielding the enantiomer (R)-(-)-2-Phenylbutyric acid in good yield. This method is preferred for its simplicity and high enantioselectivity.
About
CAS No
938-79-4
English Name
(R)-(-)-2-Phenylbutyric acid
Molecular Formula
C10H12O2
Molecular Weight
164.2 g/mol
SMILES
CCC(C1=CC=CC=C1)C(=O)O
InChIKey
OFJWFSNDPCAWDK-SECBINFHSA-N
Last Updated: 2025-10-22 19:24
