Compound Q&A

How is 6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)-4(3H)-quinazolinone (CAS: 56287-74-2) typically synthesized?

Answer

6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)-4(3H)-quinazolinone
6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)-4(3H)-quinazolinone (CAS: 56287-74-2) is typically synthesized via a condensation reaction of 2-(fluoromethyl)-3-(2-methylphenyl)-4(3H)-quinazolinone with an amino-containing compound. Commonly, the reaction is catalyzed by a mild base such as triethylamine. The yield is typically around 70-80%, and the reaction is carried out under mild conditions to ensure high selectivity.

About

CAS No 56287-74-2
English Name 6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)-4(3H)-quinazolinone
Molecular Formula C16H14FN3O
Molecular Weight 283.31 g/mol
SMILES CC1=CC=CC=C1N2C(=NC3=C(C2=O)C=C(C=C3)N)CF
InChIKey VDOSWXIDETXFET-UHFFFAOYSA-N
Last Updated: 2025-10-22 12:37

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