6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)-4(3H)-quinazolinone(CAS: 56287-74-2)

6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)-4(3H)-quinazolinone (CAS: 56287-74-2) has a crystalline form and a molecular weight of approximately 311.15 g/mol. It has low solubility in water but is soluble in common organic solvents like DMSO and DMF. This compound shows moderate reactivity, particularly in nucleophilic substitution reactions. It is stable under normal conditions but should be stored in a cool, dry place away from direct sunlight.

6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)-4(3H)-quinazolinone (CAS: 56287-74-2) is typically synthesized via a condensation reaction of 2-(fluoromethyl)-3-(2-methylphenyl)-4(3H)-quinazolinone with an amino-containing compound. Commonly, the reaction is catalyzed by a mild base such as triethylamine. The yield is typically around 70-80%, and the reaction is carried out under mild conditions to ensure high selectivity.

6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)-4(3H)-quinazolinone (CAS: 56287-74-2) finds applications in the pharmaceutical industry, particularly in the development of anti-inflammatory and anticancer drugs. It is also used in the polymer industry for the synthesis of advanced materials. Additionally, it has potential uses in the sensor and semiconductor industries due to its electronic properties.

When handling 6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)-4(3H)-quinazolinone (CAS: 56287-74-2), it is important to use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and lab coats. Store the compound in a fume hood to minimize exposure to air and potential volatiles. Spills should be immediately cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.