Compound Q&A

How is heparin (CAS: 9005-49-6) typically synthesized?

Answer

Heparin
Heparin (CAS: 9005-49-6) is typically synthesized from porcine or bovine intestinal mucosa. The process involves extraction, purification, and depolymerization to obtain a suitable molecular weight range for clinical use. Enzymatic depolymerization using heparin lyase is a common method to achieve the desired properties. The yield and selectivity of the synthesis depend on the specific enzymatic conditions and purification steps.

About

CAS No 9005-49-6
English Name Heparin
Molecular Formula C14H25N2O20S3
Molecular Weight 637.54 g/mol
EINECS 232-681-7
SMILES CO[C@H]1O[C@H](COS(=O)(=O)O)[C@H]([C@@H]([C@H]1NS(=O)(=O)O)O)O[C@@H]1O[C@@H](C(=O)O)[C@H]([C@@H]([C@H]1OS(=O)(=O)O)O)OC.[N]
InChIKey CKSLBFBQMMRQLA-LBUDAAJFSA-N
Last Updated: 2025-10-22 12:37

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