Compound Q&A
How is 4-Aminonicotinaldehyde (CAS: 42373-30-8) typically synthesized?
Answer
4-Aminonicotinaldehyde (CAS: 42373-30-8) can be synthesized by the acylation of nicotinaldehyde with ammonia. Commonly, nicotinaldehyde is refluxed with ammonium hydroxide in an aqueous medium under basic conditions. The reaction yield can reach up to 70-80% with good selectivity. This method is straightforward and suitable for laboratory-scale production.
About
CAS No
42373-30-8
English Name
4-Aminonicotinaldehyde
Molecular Formula
C6H6N2O
Molecular Weight
122.13 g/mol
SMILES
C1=CN=CC(=C1N)C=O
InChIKey
GTPZHMGXKZIHKW-UHFFFAOYSA-N
Last Updated: 2025-10-22 12:37
