Compound Q&A
How is (1S)-1-(2,4-difluorophenyl)ethan-1-amine (CAS: 845252-02-0) typically synthesized?
Answer
(1S)-1-(2,4-Difluorophenyl)ethan-1-amine can be synthesized through a multistep process involving the synthesis of 2,4-difluorophenyl chloroformate followed by condensation with ethylamine. The reaction requires conditions that favor the formation of the desired stereoisomer. The yield is generally moderate, around 70-80%, with high purity achievable through recrystallization.
About
CAS No
845252-02-0
English Name
(1S)-1-(2,4-difluorophenyl)ethan-1-amine
Molecular Formula
C8H9F2N
Molecular Weight
157.16 g/mol
SMILES
Fc1ccc(c(c1)F)[C@@H](N)C
InChIKey
VBPKWFKAYDHOQW-YFKPBYRVSA-N
Last Updated: 2025-10-22 12:37
