How is 1,2,3-Trifluoro-5-iodobenzene (CAS: 170111-66-0) typically synthesized?

1,2,3-Trifluoro-5-iodobenzene can be synthesized via a multi-step process involving the introduction of fluorine and iodine into a benzene ring. A common approach involves the use of trifluoromethylating reagents like trifluoromethyl iodide and a halogenating agent like N-bromosuccinimide (NBS) to introduce the trifluoro and iodine functionalities, respectively. The reaction conditions and catalysts are crucial for achieving high selectivity and yield.