Compound Q&A

How is 2'-Deoxy-N-[(dimethylamino)methylene]guanosine (CAS: 17331-13-4) typically synthesized?

Answer

2'-Deoxy-N-[(dimethylamino)methylene]guanosine
2'-Deoxy-N-[(dimethylamino)methylene]guanosine is typically synthesized through a multistep process involving the methylation of guanine followed by the installation of the 2'-deoxyribose moiety. Common reagents include dimethylamine and dimethyl sulfate. The overall yield is moderate to good, and the reaction is carried out under mild conditions to ensure selectivity.

About

CAS No 17331-13-4
English Name 2'-Deoxy-N-[(dimethylamino)methylene]guanosine
Molecular Formula C13H18N6O4
Molecular Weight 322.33 g/mol
SMILES CN(C)C=NC1=NC2=C(C(=O)N1)N=CN2C3CC(C(O3)CO)O
InChIKey ZXECVVVXPHBGGX-NMSRVTMWSA-N
Last Updated: 2025-10-22 12:37

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