Compound Q&A

Are there alternatives to Avatrombopag (CAS: 570406-98-3) in synthesis?

Answer

Avatrombopag
Avatrombopag (CAS: 570406-98-3) has several analogs and structural isomers that can serve as alternatives in synthesis. Common alternatives include TPO agonists with similar mechanisms of action, such as eltrombopag and crizotinib, which can be used as substitutes depending on the specific requirements of the synthesis.

About

English Name Avatrombopag
Molecular Formula C29H34Cl2N6O3S2
Molecular Weight 649.67 g/mol
SMILES C1CCC(CC1)N2CCN(CC2)C3=C(N=C(S3)NC(=O)C4=CC(=C(N=C4)N5CCC(CC5)C(=O)O)Cl)C6=CC(=CS6)Cl
InChIKey OFZJKCQENFPZBH-UHFFFAOYSA-N
Last Updated: 2025-10-21 00:33

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