Compound Q&A
How is 3-Amino-2-methoxyisonicotinic acid (CAS: 870997-81-2) typically synthesized?
Answer
3-Amino-2-methoxyisonicotinic acid can be synthesized by reacting nicotinic acid with methylamine followed by methylation. Alternatively, it can be prepared by the nucleophilic substitution of methoxy group on nicotinic acid. The reaction typically requires a mild base as a catalyst and provides good yield (up to 85%) with high selectivity.
About
CAS No
870997-81-2
English Name
3-Amino-2-methoxyisonicotinic acid
Molecular Formula
C7H8N2O3
Molecular Weight
168.15 g/mol
SMILES
COc1c(c(ccn1)C(=O)O)N
InChIKey
ABVDQGNEDSKBLA-UHFFFAOYSA-N
Last Updated: 2025-10-20 00:35
