Compound Q&A
How is Ethyl 7-chloro-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate (CAS: 100491-29-0) typically synthesized?
Answer
Ethyl 7-chloro-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate is typically synthesized through a multi-step process involving protective group chemistry, coupling reactions, and deprotection. The key steps include the formation of an intermediate from 2,4-difluorophenyl and a naphthyridine core, followed by chlorination and the introduction of the ethyl ester group.
About
CAS No
100491-29-0
English Name
Ethyl 7-chloro-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate
Molecular Formula
C17H10ClF3N2O3
Molecular Weight
382.73 g/mol
SMILES
CCOC(=O)C1=CN(C2=NC(=C(C=C2C1=O)F)Cl)C3=C(C=C(C=C3)F)F
InChIKey
JLSXYCZRMYCIMY-UHFFFAOYSA-N
Last Updated: 2025-10-20 00:35
