Ethyl 7-chloro-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate(CAS: 100491-29-0)

Ethyl 7-chloro-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate is a crystalline compound with a molecular weight of approximately 460.04 g/mol. It is sparingly soluble in water but more soluble in organic solvents like ethanol and acetonitrile. The compound is chemically reactive, particularly towards nucleophiles, and is known for its stability under neutral to slightly acidic conditions.

Ethyl 7-chloro-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate is typically synthesized through a multi-step process involving protective group chemistry, coupling reactions, and deprotection. The key steps include the formation of an intermediate from 2,4-difluorophenyl and a naphthyridine core, followed by chlorination and the introduction of the ethyl ester group.

Ethyl 7-chloro-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate is primarily used in the pharmaceutical industry for the development of therapeutic agents. It has potential applications in sensor technology and semiconductor manufacturing due to its unique chemical structure and physicochemical properties.

When handling Ethyl 7-chloro-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate, it is crucial to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Ensure that the work is conducted in a well-ventilated area or a fume hood. Spills should be handled with caution, using spill kits or absorbent materials, and the area should be cleaned with a suitable solvent. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and safety measures.