Compound Q&A

How is 2-Phenyl-1,3-benzoxazole (CAS: 833-50-1) typically synthesized?

Answer

2-Phenyl-1,3-benzoxazole
2-Phenyl-1,3-benzoxazole can be synthesized via condensation of phenylglyoxal with phenol in the presence of an acid catalyst, such as sulfuric acid. Alternatively, it can be prepared by the reaction of phenylisoxazole with acetyl chloride. The yield is typically around 70-80%, and the process involves careful control of temperature and reaction time to achieve high product purity.

About

CAS No 833-50-1
English Name 2-Phenyl-1,3-benzoxazole
Molecular Formula C13H9NO
Molecular Weight 195.22 g/mol
SMILES C1=CC=C(C=C1)C2=NC3=CC=CC=C3O2
InChIKey FIISKTXZUZBTRC-UHFFFAOYSA-N
Last Updated: 2025-10-20 00:35

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