Compound Q&A
How is Methyl 4-aminothiophene-2-carboxylate (CAS: 89499-43-4) typically synthesized?
Answer
Methyl 4-aminothiophene-2-carboxylate (CAS: 89499-43-4) can be synthesized through a one-pot procedure involving thiophenol, methyl acetoacetate, and a catalytic amount of an acid like sulfuric acid. The reaction yields the desired product with good selectivity and up to 85% yield. This method is commonly used in organic synthesis laboratories for the preparation of functionalized thiophenes.
About
CAS No
89499-43-4
English Name
Methyl 4-aminothiophene-2-carboxylate
Molecular Formula
C6H7NO2S
Molecular Weight
157.19 g/mol
SMILES
COC(=O)C1=CC(=CS1)N
InChIKey
HCRQNZWIOUMCOW-UHFFFAOYSA-N
Last Updated: 2025-10-20 00:35
