Methyl 4-aminothiophene-2-carboxylate(CAS: 89499-43-4)

Methyl 4-aminothiophene-2-carboxylate (CAS: 89499-43-4) is a solid with a crystalline form. Its molecular weight is approximately 184.2 g/mol. This compound is slightly soluble in water and more soluble in organic solvents like methanol and ethanol. It is known for its reactivity towards nucleophilic substitution reactions and can form stable ester and amide bonds. It has a melting point around 160-162°C and a boiling point of approximately 270°C at 10 mmHg.

Methyl 4-aminothiophene-2-carboxylate (CAS: 89499-43-4) can be synthesized through a one-pot procedure involving thiophenol, methyl acetoacetate, and a catalytic amount of an acid like sulfuric acid. The reaction yields the desired product with good selectivity and up to 85% yield. This method is commonly used in organic synthesis laboratories for the preparation of functionalized thiophenes.

Methyl 4-aminothiophene-2-carboxylate (CAS: 89499-43-4) finds application in various industries. It is used in pharmaceuticals for the synthesis of biologically active compounds. In the polymer industry, it serves as a monomer for preparing functionalized polymers. Additionally, it is utilized in the development of sensors and semiconductors due to its unique electronic properties.

When handling Methyl 4-aminothiophene-2-carboxylate (CAS: 89499-43-4), it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. This compound should be handled in a well-ventilated area or a fume hood to avoid inhalation of fumes. Spills should be cleaned up with appropriate absorbents and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal information.