Compound Q&A
How is (2-Fluoro-6-hydroxyphenyl)boronic acid (CAS: 1256345-60-4) typically synthesized?
Answer
(2-Fluoro-6-hydroxyphenyl)boronic acid is commonly synthesized via a multistep process involving the protection of a hydroxy group, introduction of the fluoro substituent, and subsequent boronation. Common reagents include boronic acids, boronates, and boronate esters, often in the presence of a palladium catalyst. The yield is typically around 75-85%, with high selectivity for the desired product.
About
CAS No
1256345-60-4
English Name
(2-Fluoro-6-hydroxyphenyl)boronic acid
Molecular Formula
C6H6BFO3
Molecular Weight
155.92 g/mol
SMILES
OB(c1c(O)cccc1F)O
InChIKey
FPXQHZPCFRQWCP-UHFFFAOYSA-N
Last Updated: 2025-10-20 00:35
