Compound Q&A
How is Methyl (3R)-3-pyrrolidinecarboxylate hydrochloride (CAS: 874964-22-4) typically synthesized?
Answer
Methyl (3R)-3-pyrrolidinecarboxylate hydrochloride is synthesized by the reaction of (S)-3-methylpyrrolidine with acetic anhydride followed by hydrolysis with hydrochloric acid. The reaction is typically carried out in anhydrous conditions to minimize side reactions. The yield is around 85-90%, and the use of suitable catalysts can improve selectivity and efficiency.
About
CAS No
874964-22-4
English Name
Methyl (3R)-3-pyrrolidinecarboxylate hydrochloride (1:1)
Molecular Formula
C6H12ClNO2
Molecular Weight
165.62 g/mol
SMILES
Cl.COC(=O)[C@@H]1CCNC1
InChIKey
VVBSXSVVMNGQIN-NUBCRITNSA-N
Last Updated: 2025-10-20 00:35
