Compound Q&A

How is Onalespib (CAS: 912999-49-6) typically synthesized?

Answer

Onalespib
Onalespib is synthesized through a multi-step process involving coupling reactions, alkylation, and reduction steps. The synthesis requires the use of various catalysts and reagents such as triphenylphosphine and sodium hydride. The overall yield is moderate, and the reaction conditions must be strictly controlled to achieve high selectivity and purity.

About

English Name Onalespib
Molecular Formula C24H31N3O3
Molecular Weight 409.53 g/mol
SMILES CC(C)C1=CC(=C(C=C1O)O)C(=O)N2CC3=C(C2)C=C(C=C3)CN4CCN(CC4)C
InChIKey IFRGXKKQHBVPCQ-UHFFFAOYSA-N
Last Updated: 2025-10-20 00:35

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