Compound Q&A
How is 5-(4-Chlorophenyl)-1H-pyrrolo[2,3-B]pyridine (CAS: 918516-27-5) typically synthesized?
Answer
![5-(4-Chlorophenyl)-1H-pyrrolo[2,3-B]pyridine](https://static.chemtradehub.com/structs/918/918516-27-5-6e98.webp "5-(4-Chlorophenyl)-1H-pyrrolo[2,3-B]pyridine")
5-(4-Chlorophenyl)-1H-pyrrolo[2,3-B]pyridine is typically synthesized via the chlorination of 1-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-5(4H)-one. This process involves the use of a Lewis acid catalyst, such as aluminum chloride, in a suitable solvent like dichloromethane. The reaction is sensitive to temperature and requires careful control to achieve high yield and selectivity.
About
CAS No
918516-27-5
English Name
5-(4-Chlorophenyl)-1H-pyrrolo[2,3-B]pyridine
Molecular Formula
C13H9ClN2
Molecular Weight
228.68 g/mol
SMILES
C1=CC(=CC=C1C2=CN=C3C(=C2)C=CN3)Cl
InChIKey
AIRHBAXIGSQPNX-UHFFFAOYSA-N
Last Updated: 2025-10-20 00:35
![5-(4-Chlorophenyl)-1H-pyrrolo[2,3-B]pyridine — HePeng （ ShangHai ） Biotechnology Co Ltd](https://static.chemtradehub.com/suppliers/67ceccf22b2de6e8e95a5e0f/67ceccf22b2de6e8e95a5e0f-logo.webp){kind=logo}