Compound Q&A

How is (3-Hydroxyadamantan-1-yl)(oxo)acetic acid (CAS: 709031-28-7) typically synthesized?

Answer

(3-Hydroxyadamantan-1-yl)(oxo)acetic acid
(3-Hydroxyadamantan-1-yl)(oxo)acetic acid (CAS: 709031-28-7) can be synthesized through the condensation of 3-hydroxyadamantan-1-one with acetic anhydride. The reaction is carried out in the presence of a catalyst like p-toluenesulfonic acid (p-TsOH) to improve yield and selectivity. The product is then isolated by recrystallization from an appropriate solvent.

About

English Name (3-Hydroxyadamantan-1-yl)(oxo)acetic acid
Molecular Formula C12H16O4
Molecular Weight 224.26 g/mol
SMILES C1C2CC3(CC1CC(C2)(C3)O)C(=O)C(=O)O
InChIKey UDKIRRNUAXWHTO-UHFFFAOYSA-N
Last Updated: 2025-10-20 00:35

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